A Research Study On Breast Cancer - 1308 Words

Introduction Breast Cancer is on the fore-front of modern tumor research and scientists are continually seeking for new ways to treat and prevent cancer progression. Current treatments by hormone-dependent drugs like Tamoxifen and Raloxifene focus on estrogen receptor inhibition in mammary and endometrial cell lines. This group of drugs are known as selective-estrogen receptor modulators or SERMS, which are effective in estrogen-receptor positive (ER+) and hormone-estrogen receptor 2 positive (HER2+) breast cancers . Currently , researchers have turned their attention to retinoids – materials similar to vitamin A, which control cell proliferation and differentiation, apoptosis, and gene suppression in both normal and cancerous epithelial tissues. Specifically, fenretinide, a synthetic retinoid, is of particular interest for treating epithelial breast cancer after yielding positive results in inducing apoptosis in in vitro, in vivo, and clinical trials. Fenretinide’s exact function s in the cell for chemo-preventative use are still being discovered, such as its supposed relationship with the nuclear retinoid receptors RARÉ £ and RXR ÃŽ ², which control cell growth and apoptosis, and its effect on insulin-growth factor (IGF) receptors, which are high risk factors for breast cancer. Fenretinide has been discovered inducing cell death by other novel means through receptor-independent mechanisms . Combination therapy of fenretinide and Tamoxifen together has shown greater effect onShow MoreRelatedA Research Study On Breast Cancer2138 Words   |  9 Pages Breast Cancer accounts for more than 20 percent of cancer in women, and is the primary cause of cancer death among women globally.1 Despite extensive scientific research on the disease, the outlook on a cure arguably remains poor. While some breast cancer survivors and women at high risk remain hopeful that soy intake will reduce the risk or even cure cancer, the recommendations are conflicting. For decades, the relationship between soy foods, supplements, phytoestrogen intake and cancer hasRead MoreA Research Study On Breast Cancer981 Words   |  4 PagesIn this case study we have Sarah a forty-two-year-old woman who has breast cancer which has metastasized to her lungs. Despite having had multiple tumors removed the cancer has returned. Sarah’s oncologist, Greg, recommends that she take part in a double blind experimental drug trial in an effort to slow the occurrence of more tumors. Greg explains that the risks of the drug are not entirely known; the drug won’ t cure her cancer but may slow its progression, it may leave her extremely fatiguedRead MoreA Research Study On Breast Cancer1702 Words   |  7 PagesIntroduction Breast cancer is one of the leading causes of high mortality and morbidity in women population worldwide. Up to date, no effective breast cancer treatment has been developed and this has motivated academic scientists for the quest for alternative drugs and the discovery of drug targets. Increasing evidence suggests that carotenoids, which are micronutrients in fruit and vegetables, reduce breast cancer risk [1]. Previous findings suggest a protective role of ÃŽ ±-carotene, ÃŽ ²-carotene,Read MoreBreat Cancer Screening Essay1514 Words   |  7 PagesBREAST CANCER SCREENING DR. DANA MORTEZ ARLECIA PURVIS JULY 17, 2011 Current research shows mammograms are stronger than in the past. 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Tumor is when there is swellingRead MoreThe Issue Of Breast Cancer830 Words   |  4 PagesThe issue of breast cancer affecting many individuals is a growing one. At the present time period it is now found that one in every eight women will be told they have breast cancer (â€Å"National Breast Cancer Foundation†, 2012). Therefore there is a significant amount of research going into this area. In addition, to the large amount of women and smaller amount of men who will be potentially diagnosed with breast cancer has become a global burden because those with metastatic cancer will eventuallyRea d MoreThe Survival Rates Of Breast Cancer1373 Words   |  6 Pages Breast Cancer is the most common misfortune in women and second leading cause of death by cancer. Today, woman with breast cancer have a 90% chance of surviving for five years post-diagnosis. However, African American women have a national survival rate of 79%. Socioeconomic barriers and lack of access to health services have crippled African American women in breast cancer advancements. Studies have show that African American women tend to be diagnosed with a higher-stage of cancer because ofRead MoreThe Importance Of Breast Cancer Treatment934 Words   |  4 PagesBreast cancer treatment depends on many factors such as the location of the cancer, the size, if it’s spread and the patient’s general health. Also, treatment currently includes surgery, chemotherapy, radiotherapy, hormonal therapy and targeted cancer drugs (Cancer Research UK, 2017a). Further, surgery includes lumpectomy which removes just the cancerous area in an attempt to keep the majority of the breas t tissue and has a much shorter recovery time and mastectomy which removes the entirety of theRead MoreA Brief Note On The North Fork Of Long Island1726 Words   |  7 Pagesweeds, these commodities would be much harder to come by. Chemicals such as PCB’s, PHA’s, and the now banned DDT were all once used on these fertile farmlands of Long Island and since then may be a direct factor to the rise in cancer rates on Long Island, especially breast cancer. In the agricultural industry, one of the most common ways to treat crops is by a fogging method. With this method, a large factor goes through the crops with tanks of whatever chemical pesticide or fungicide they may be usingRead MoreBreast Cancer : A Common Malignancy1204 Words   |  5 PagesBreast cancer is the most common malignancy in the UK, accounting for 15% of all diagnosed cancers, affecting around 50,000 women and 350 men, leading to just under 12,000 deaths in 11/12.1,2 The risk of getting breast cancer is linked to increased age, gender genetics (BRCA 1 BRCA 2 gene mutations). Lifestyle factors that also increase the incidence of breast cancer (around 27% each year) are; Oestrogen exposure, being overweight/obese, high alcohol intake, tobacco smoke, oral contraceptives

The And International Monetary Fund - 1501 Words

Living Below the Line The majority of the world’s nations and people are in a state of poverty. Most in-debt nations are a result of guidelines set by global establishments that use the nation’s desperation to their advantage. Also, many causes of hunger result in poverty. Additionally, the world as a whole has spent unfathomable amounts of money for wants, when achieving basic necessities for developing countries is far less. Poverty would not have to exist if the developed world was not greedy to satisfy and only concerned with their own wants. As an outcome of neoliberalism circumstances set by global institutions, such as the World Bank and International Monetary Fund (IMF), many nations have been in debt and in poverty since they†¦show more content†¦As a result, â€Å"governments then need to increase exports just to keep their currencies stable [and in order to do so,] governments therefore must spend less, reduce consumption†¦Ã¢â‚¬  (Shah). In re ality, the financial â€Å"assistance† provided actually worsens the poverty and keeps the nation for attaining financial stability. Another notion is for developing nations to advertise their resources to have investors interested and to bring in money, however many other developing nations might advertise the same resource. The battle between the nations can lead to a price war. Poor countries need to pay off their debts and the best way to do is to export more resources. Developing nations desperately need the money and to obtain it â€Å"[they enter the global market] before they are economically and socially stable and ready—and told to concentrate on similar cash crops and commodities as others, the situation resembles a large-scale price war† (Shah). Once again, this favours the West instead of making a significant change in the status of poor regions. The developing countries will lower their prices to make them more appealing to potential investors. As a realistic solution, I would suggest for governments to put laws that would allow them to have more control over their own resources and industries. They need to set laws where the developing region’s government is required to have a certain level of involvement in global affairs. In addition to the laws, I believe that the

Effects of Globalization on an Organization-Sample for Students

Question: Discuss about the Challenges faced by the Global Organizations. Answer: Introduction- The international business is facing some severe attacks of auditing and accounting at the global platform. This is happening because of globalization, which has integrated multi business at just one place. The integration of business has created many challenges to cope of with. Accounting and auditing are one of those challenges, which are troubling the business experience of global organizations (Knechel and Salterio 2016). Being a student of Business Administration, the journey of research over numerous weeks and the particular assignment works has proved to be an extremely educative experience for me. The two assignments had covered the accounting challenges that the global organizations face today and the challenges for the professionals in the rapid changing business environment. The first assignment had covered the literature section based on available secondary resources. On other hand, the second assignment had covered the proposal on the subject topic. Both these assignment s have proved to be exceedingly informative to me. These assignments have actually provided me a viewpoint of a realistic trade operations and the international business environment. Effectiveness of Learning Process- The understanding of the international business environment and the trouble faced by the business professionals is extremely effective for my academic course, program, my career and life. Following are the utilization of the courses and the researches on my course, program, career and life: Course- The first two assignments have not only helped me in understanding the business complexities at the global platform but it has also made me think practical on the business nature of the global organizations. Most importantly, this has opened me towards a worldview, which is of high importance for a successful career and life. Program- Some of the issues such as monetary issues, shortcomings in the inflow cash, corporate world, financial reports of international organizations, influencing local government policies of different region and different other external factors (Mala and Chand 2012). Career- The global business relationships and the difficulties, which they are facing have in them some very useful knowledge for my future reference. Moreover, with the help of such knowledge I can benefit my organization and myself as well. It is very important to know the challenges the contemporary global business is facing because this would strengthen my competitive capabilities. Nevertheless, competitive skills are highly admired in top organizations. Life- The amount of knowledge, which the two assignments have provided to me, is extremely helpful for my life as well. One can never enjoy a healthy life until and unless it does not have its utmost control on the different level of challenges that it face at the organizational level. Knowledge process- The processing of knowledge in the provided assignment was done with the help of some researches, which is further divided into two categories such as primary research and the secondary research. The proposal had helped me learnt on how to use the most appropriate secondary resources to find the most relevant requirements. The proposal work did also help me learn on how to conduct a primary research. Moreover, the primary research is something that is being gathered by taking interviews of the selective business professionals as well as an online survey (Bryman and Bell 2015). Learning outcomes- Both the assignments have focussed their concentration on finding the global issues of auditing and the accounting. It also focussed on the different taxation rules in the different global regions (Bhasin 2015). The first assignment has tried to find the problems with the help of secondary resources such as Books, Journals, website articles etc. The second assignment has tried to research the problem area with the help of primary resources, which can be a structured interview, an online survey etc (Polonsky and Waller 2014). Both the assignments have not only helped me know the existing complexities in the international business platform but it have also taught me on how to do research works on topic as such. Evaluation- The provided assignments have discussed some of the business issues, which the global business is facing. The global business is facing some challenges in terms of accounting and auditing works. This is because that different region in world has their separate rules and regulations for taxation (Ngwakwe 2012). Both the assignment are highly informative not in terms of business but in terms of education rather. This is because that both the assignments have tried to research the global problem of accounting and auditing in the international business (Davies and Green 2013). They have highlighted a global issue but they have not given detailed information of the same. Both the provided assignments are rather educative, which is extremely important for students pursuing Business Administration degree in Universities. The first assignment has tried to research the problem with the help of secondary resources such as journals, books and newspaper articles. The second assignment on other h and has tried to research the problem with the help of various primary resources, which can be any such as a structured interview, an online survey etc (Collis and Hussey 2013). Reason for the research The reason for the research can be anything for different students; however, this topic has personally ignited my interest towards it. This is because of such reasons I decided to pursue my interest by conducting a thorough research on the topic. The subject matter has excited my desire and I felt that I should conduct a research on the topic. This is for such reason I prepared this research proposal to get approval on it. Knowledge application and conclusion- This research and the derived knowledge with the help of some research are very helpful for the global companies. It is also helpful for companies who are taking initiatives with their new business. The research would try to find the possible information regarding the global challenge in the form of accounting and the auditing. Nevertheless, this would attract some more future research works; however, the findings of my research would definitely help the global organizations. The global organizations are facing some serious challenges in the form of accounting and auditing. This is because of the differing rules of taxation in such regions. The worked out assignments have tried to put forward a proposal for the research on the chosen topic. Moreover, findings of the research would definitely help the global organizations. It would help the Business Administration students in enriching their knowledge of the subject matter as well. References- Bhasin, M.L., 2015. Corporate accounting fraud: A case study of Satyam Computers Limited. Bryman, A. and Bell, E., 2015.Business research methods. Oxford University Press, USA. Collis, J. and Hussey, R., 2013.Business research: A practical guide for undergraduate and postgraduate students. Palgrave macmillan. Davies, H. and Green, D., 2013.Global Financial Regulation: The Essential Guide (Now with a Revised Introduction). John Wiley Sons. Knechel, W.R. and Salterio, S.E., 2016.Auditing: assurance and risk. Routledge. Mala, R. and Chand, P., 2012. Effect of the global financial crisis on accounting convergence.Accounting Finance,52(1), pp.21-46. Ngwakwe, C.C., 2012. Rethinking the accounting stance on sustainable development.Sustainable Development,20(1), pp.28-41. Polonsky, M.J. and Waller, D.S., 2014.Designing and managing a research project: A business student's guide. Sage Publications